王彬;宁黔冀;王倩;彭玮;郝彤;孙金生;

• 1:河南师范大学生命科学学院
• 2:天津师范大学生命科学学院
• 3:天津师范大学天津市动植物抗性重点实验室

摘要(Abstract)：

为了研究中华绒螯蟹的免疫蛋白作用机制,在已构建的中华绒螯蟹蛋白互作网络基础上,采用邻接节点注释方法对其全局网络进行细胞组分注释,为网络的903个未定位蛋白中的830个添加了GO注释,占未定位蛋白的91.9%.从中华绒螯蟹蛋白互作网络中提取了包含142个蛋白和158条蛋白互作关系的免疫互作网络,并且结合GO细胞组分注释信息,得到了其中62个免疫蛋白的细胞组分定位.通过对细胞定位的分析发现,中华绒螯蟹的免疫蛋白多位于膜结构、细胞核和细胞骨架中.

关键词(KeyWords)： 中华绒螯蟹;蛋白互作网络;邻接节点注释;免疫蛋白

Abstract:

Keywords:

基金项目(Foundation): 国家高技术研究发展计划(863计划)资助项目(2012AA10A401,2012AA092205);; 国家重点基础研究发展计划(973计划)资助项目(2012CB114405);; 国家自然科学基金资助项目(21106095);; 国家科技支撑计划资助项目(2011BAD13B07,2011BAD13B04);; 天津市应用基础与前沿技术研究计划资助项目(15JCYBJC30700);; 天津市“三年引进千名高层次人才”计划资助项目(5KQM110003);; 天津市“131”创新型人才培养工程资助项目(ZX110170);; 天津师范大学青年教师学术创新推进计划资助项目(52XC1403)

作者(Author): 王彬;宁黔冀;王倩;彭玮;郝彤;孙金生;

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